.NET Nuke Vs SharePoint

Dotnet Nuke --Open source. It’s a website creation tool that makes our job easy .This is developed using ASP.NET .NET nuke is recommended for small applications like personal website, for the applications where we can minimize the cost .Developer’s develope .Net Nuke Module .

A Person with little or no IT experience means a novice can work directly on it.

Share Point-- Need to have to buy license from Microsoft
It’s collaboration tool. Portal .MOSS 2007 also ASP.NET application that runs on top of ASP.NET 2.0. It uses HTTP Modules and HTTP Handlers as the application. Sql Server stores all ASPX Pages.You can extend Share Point or create workflow related applications or WSPs using Visual Studio IDE. Using Share Point you can extend an existing application to another web application so that information can be shared. Each application can have its own authentication mechanism. Share point applications are good for enterprise applications .Enterprises can create central application framework using Share Point Developers Develop Web Parts .An hands on experienced guy is required. If you need tight integration with MS Office, document library with version control or work flow enabled application, share point is the only choice.
At a Glance

.NET Nuke	SharePoint
Open Source	Need License
Need IIS ,Vistual Studio to develop and .Net nuke installation	Need Windows Server 2003/2008, Visual Studio, .NETramework, WSS ,SPS and Sharepoint Server
WebSite Creation Tool	Colloboration Portal
Used for developing .NET Nuke Modules	Used for Developing Webparts
A smart guy with no IT experience can work on it	Experience is required to develope or work on sharepoint
Good for Content based  or static or personal web applications (Can manage the content)	Good for enterprize applications where we can collborate the team in the portal
We can have anonymous access or forms authentication	We can have windows or Forms authentication
Workflow application developement  is not  possible	Workflow application developement  is possible
Document Management, Check in ,Check out, Version control is a limitation	Document Management, Check in ,Check out, Version control is in built
DNN Skins make the user to design layout of the page , can get good look and feel, easy to customize a skin	Uses themes in WSS /Custom CSS Files in SPS
No Singlesign on ,Enterprize search	Sinlge sign on and Enterprize Search

Finally to choose, it depends on our requirement, if your application needs tight integration to MS Office, that should allow version control, uses Excel Services and Business Intelligence, Collaborate your team at single place then Share Point would be right choice. If you cannot afford so much cost and application is related to content or SEO, like static, personal websites then you can go for .NET Nuke

Ps: the Term “Share Point “here refer to SPS and WSS